In the realm of chemical analysis, even the slightest deviation can compromise experimental outcomes and derail research progress. Achieving absolute precision demands meticulous attention to detail. One key to reliable acid-base titration lies in an unassuming yet indispensable reagent: HPLC-grade potassium hydrogen phthalate (KHP).
Uncompromising Quality for Scientific Rigor
Potassium hydrogen phthalate (KHP), a white crystalline powder readily soluble in water, serves as a monopotassium salt of phthalic acid. This compound has become fundamental in analytical chemistry, particularly for high-performance liquid chromatography (HPLC) and acid-base titrations.
The HPLC-grade variant meets stringent purity standards exceeding 99%, with minimal impurities that could interfere with analytical results. This level of quality makes it indispensable for pharmaceutical analysis, food testing, and environmental monitoring applications.
Technical Specifications
- Product Code: P 2268
- CAS Number: 877-24-7
- Molecular Formula: C 8 H 5 KO 4
- Molecular Weight: 204.22 g/mol
- Appearance: White powder
- Melting Point: 295-300°C
Packaging Options
| Package Size | Price (CNY) | Price (USD) |
|---|---|---|
| 250 g | 693.00 | 9.63 |
| 500 g | 1080.00 | 15.00 |
| 4 × 25 kg | Available upon request | |
Scientific Applications
KHP demonstrates remarkable versatility across multiple analytical techniques:
Primary Standard for Acid-Base Titration
Its stability, non-hygroscopic nature, and precise weighability make KHP the preferred primary standard for preparing reference solutions. These standardized solutions enable accurate determination of unknown acid or base concentrations.
HPLC Buffer Component
In chromatographic separations, KHP serves as an effective pH regulator for mobile phases. Proper buffering enhances peak resolution and separation efficiency, critical for obtaining reliable HPLC data.
pH Meter Calibration
Standard KHP solutions provide reference points for calibrating pH measurement devices, ensuring accurate readings in sensitive experiments.
Analytical Reagent
The compound's acidic properties facilitate quantitative analysis of metal ions through specific chemical reactions.
Safety Considerations
- Use personal protective equipment including gloves and eye protection
- Avoid dust inhalation
- Flush exposed areas with copious water if contact occurs
- Follow standard laboratory safety protocols for storage and handling
Quality Assurance
The production of HPLC-grade KHP involves rigorous quality control measures from raw material selection through final packaging. This ensures batch-to-batch consistency and reliability for critical applications.
Technical support teams provide expertise to address analytical challenges, while efficient logistics networks guarantee timely delivery of materials.
Conclusion
HPLC-grade potassium hydrogen phthalate stands as a cornerstone reagent for precision analytical chemistry. Its exceptional purity, stability, and multifunctionality support accurate measurements across diverse scientific disciplines, from pharmaceutical research to environmental analysis.
